Other terms
Anti Glomerular Basement Membrane Disease,Goodpasture Syndrome,Syndrome, Goodpasture,Anti-GBM Disease,Anti GBM Disease,Goodpasture's Syndrome,Goodpastures Syndrome,Syndrome, Goodpasture's,Lung Purpura with Nephritis
Description
Anti-Glomerular Basement Membrane Disease: An autoimmune disease of the KIDNEY and the LUNG. It is characterized by the presence of circulating autoantibodies targeting the epitopes in the non-collagenous domains of COLLAGEN TYPE IV in the basement membranes of kidney glomeruli (KIDNEY GLOMERULUS) and lung alveoli (PULMONARY ALVEOLI), and the subsequent destruction of these basement membranes. Clinical features include pulmonary alveolar hemorrhage and glomerulonephritis.
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