Other terms
Amiloride Hydrochloride, Anhydrous,Anhydrous Amiloride Hydrochloride,Hydrochloride, Anhydrous Amiloride,Kaluril,Alphapharm Brand of Amiloride Hydrochloride,Midamor,Modamide,Merck Sharp & Dohme Brand of Amiloride Hydrochloride,Cahill May Roberts Brand of Amiloride Hydrochloride,Merck Brand of Amiloride Hydrochloride,Amiloberag,Berolina Brand of Amiloride Hydrochloride,Amidal,Douglas Brand of Amiloride Hydrochloride,Amiduret Trom,Trom, Amiduret,Trommsdorff Brand of Amiloride Hydrochloride,Amiloride Hydrochloride,Hydrochloride, Amiloride,Midoride,Amrad Brand of Amiloride Hydrochloride
Description
Amiloride: A pyrazine compound inhibiting SODIUM reabsorption through SODIUM CHANNELS in renal EPITHELIAL CELLS. This inhibition creates a negative potential in the luminal membranes of principal cells, located in the distal convoluted tubule and collecting duct. Negative potential reduces secretion of potassium and hydrogen ions. Amiloride is used in conjunction with DIURETICS to spare POTASSIUM loss. (From Gilman et al., Goodman and Gilman's The Pharmacological Basis of Therapeutics, 9th ed, p705)
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