Other terms
Tumor Necrosis Factor alpha,Cachectin-Tumor Necrosis Factor,Cachectin Tumor Necrosis Factor,TNFalpha,TNF-alpha,Tumor Necrosis Factor,Tumor Necrosis Factor Ligand Superfamily Member 2,Cachectin,TNF Superfamily, Member 2
Description
Tumor Necrosis Factor-alpha: Serum glycoprotein produced by activated MACROPHAGES and other mammalian MONONUCLEAR LEUKOCYTES. It has necrotizing activity against tumor cell lines and increases ability to reject tumor transplants. Also known as TNF-alpha, it is only 30% homologous to TNF-beta (LYMPHOTOXIN), but they share TNF RECEPTORS.
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