Other terms
AIF Apoptosis Regulatory Protein,Apoptosis-Inducing Factor,Mitochondrial Apoptosis-Inducing Factor,Apoptosis-Inducing Factor, Mitochondrial,Mitochondrial Apoptosis Inducing Factor
Description
Apoptosis Inducing Factor: A flavoprotein that functions as a powerful antioxidant in the MITOCHONDRIA and promotes APOPTOSIS when released from the mitochondria. In mammalian cells AIF is released in response to pro-apoptotic protein members of the bcl-2 protein family. It translocates to the CELL NUCLEUS and binds DNA to stimulate CASPASE-independent CHROMATIN condensation.
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