Other terms
Protein Phosphatase-2B,Protein Phosphatase 2B,Protein Phosphatase 3,Phosphatase 3, Protein,Calcineurin B,Protein Phosphatase 3 Regulatory Subunit,Calcineurin A,Protein Phosphatase 3 Catalytic Subunit
Description
Calcineurin: A CALCIUM and CALMODULIN-dependent serine/threonine protein phosphatase that is composed of the calcineurin A catalytic subunit and the calcineurin B regulatory subunit. Calcineurin has been shown to dephosphorylate a number of phosphoproteins including HISTONES; MYOSIN LIGHT CHAIN; and the regulatory subunits of CAMP-DEPENDENT PROTEIN KINASES. It is involved in the regulation of signal transduction and is the target of an important class of immunophilin-immunosuppressive drug complexes.
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