Other terms
Kinase, eIF-2,eIF 2 Kinase,Double Stranded RNA-Dependent eIF-2 alpha Protein Kinase,Double Stranded RNA Dependent eIF 2 alpha Protein Kinase,Double Stranded RNA-Dependent Kinase (dsl),dsRNA-Activated Inhibitor,Inhibitor, dsRNA-Activated,dsRNA Activated Inhibitor,DSRNA-Dep Protein Kinase,DSRNA Dep Protein Kinase,Kinase, DSRNA-Dep Protein,Protein Kinase, DSRNA-Dep,eIF-2alpha Kinase,Kinase, eIF-2alpha,eIF 2alpha Kinase,eRF, eIF-2 Recycling Factor,eRF, eIF 2 Recycling Factor,Eukaryotic Initiation Factor 2alpha Kinase,Heme Controlled Repressor,Controlled Repressor, Heme,Repressor, Heme Controlled,Heme-Controlled Inhibitor,Heme Controlled Inhibitor,Inhibitor, Heme-Controlled,Heme-Controlled Translational Repressor,Heme Controlled Translational Repressor,Repressor, Heme-Controlled Translational,Translational Repressor, Heme-Controlled,Heme-Regulated eIF-2alpha Kinase,Heme Regulated eIF 2alpha Kinase,Kinase, Heme-Regulated eIF-2alpha,eIF-2alpha Kinase, Heme-Regulated,Hemin Controlled Repressor,Controlled Repressor, Hemin,Repressor, Hemin Controlled,Hemin-Controlled Translational Repressor,Hemin Controlled Translational Repressor,Repressor, Hemin-Controlled Translational,Translational Repressor, Hemin-Controlled,p65 Kinase,Kinase, p65,p68 Kinase,Kinase, p68,P68 Protein Kinase,Kinase, P68 Protein,Protein Kinase, P68,Protein Kinase PKR,Kinase PKR, Protein,PKR, Protein Kinase,Protein Kinase, RNA Activated,RNA-Dependent Protein Kinase,Kinase, RNA-Dependent Protein,Protein Kinase, RNA-Dependent,RNA Dependent Protein Kinase,Self-Phosphorylating Protein Kinase,Kinase, Self-Phosphorylating Protein,Protein Kinase, Self-Phosphorylating,Self Phosphorylating Protein Kinase,TIK Kinase,Kinase, TIK,DAI Protein Kinase,Kinase, DAI Protein,Protein Kinase, DAI
Description
eIF-2 Kinase: A dsRNA-activated cAMP-independent protein serine/threonine kinase that is induced by interferon. In the presence of dsRNA and ATP, the kinase autophosphorylates on several serine and threonine residues. The phosphorylated enzyme catalyzes the phosphorylation of the alpha subunit of EUKARYOTIC INITIATION FACTOR-2, leading to the inhibition of protein synthesis.
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