Protein Tyrosine Phosphatase, Non-Receptor Type 22 | Legal notice |
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Other terms
Protein Tyrosine Phosphatase, Non Receptor Type 22,Protein-Tyrosine Phosphatase Lyp,Protein Tyrosine Phosphatase Lyp,Tyrosine Protein Phosphatase, Non-Receptor Type 22,Tyrosine Protein Phosphatase, Non Receptor Type 22,Lymphoid Phosphatase,PTPase Lyp,Lyp1 PTPase,PTPase, Lyp1,Lyp2 PTPase,PTPase, Lyp2
Description
Protein Tyrosine Phosphatase, Non-Receptor Type 22: A subtype of non-receptor protein tyrosine phosphatases that is characterized by the presence of an N-terminal catalytic domain and a C-terminal PROLINE-rich domain. The phosphatase subtype is predominantly expressed in LYMPHOCYTES and plays a key role in the inhibition of downstream T-LYMPHOCYTE activation. Polymorphisms in the gene that encodes this phosphatase subtype are associated with a variety of AUTOIMMUNE DISEASES.
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