Other terms
Phosphohydrolase, PTEN,PTEN Phosphatase,Phosphatase, PTEN,Phosphatase and Tensin Homologue on Chromosome Ten Protein,PTEN Protein,MMAC1 Protein,Mutated In Multiple Advanced Cancers 1 Protein
Description
PTEN Phosphohydrolase: A lipid phosphatase that acts on phosphatidylinositol-3,4,5-trisphosphate to regulate various SIGNAL TRANSDUCTION PATHWAYS. It modulates CELL GROWTH PROCESSES; CELL MIGRATION; and APOPTOSIS. Mutations in PTEN are associated with COWDEN DISEASE and PROTEUS SYNDROME as well as NEOPLASTIC CELL TRANSFORMATION.
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