Other terms
p107, Retinoblastoma-Like Protein,Retinoblastoma-Like Protein 1,Retinoblastoma Like Protein 1,RBL1 Protein,Retinoblastoma Like Protein p107,p107 Tumor Suppressor Protein
Description
Retinoblastoma-Like Protein p107: A negative regulator of the CELL CYCLE that undergoes PHOSPHORYLATION by CYCLIN-DEPENDENT KINASES. It contains a conserved pocket region that binds E2F4 TRANSCRIPTION FACTOR and interacts with viral ONCOPROTEINS such as POLYOMAVIRUS TUMOR ANTIGENS; ADENOVIRUS E1A PROTEINS; and PAPILLOMAVIRUS E7 PROTEINS.
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