Other terms
Core Binding Factor alpha Proteins,Runx Proteins,Polyomavirus Enhancer A Binding Protein 2,Polyomavirus Enhancer Binding Protein 2, Alpha Subunit,Runt Domain Factor,Acute Myeloid Leukemia Proteins,PEBP2A Transcription Factors,Transcription Factors, PEBP2A
Description
Core Binding Factor alpha Subunits: A family of transcription factors that bind to the cofactor CORE BINDING FACTOR BETA SUBUNIT to form core binding factor. Family members contain a highly conserved DNA-binding domain known as the runt domain. They can act as both activators and repressors of expression of GENES involved in CELL DIFFERENTIATION and CELL CYCLE progression.
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