NFATC Transcription Factors

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Other terms
Transcription Factors, NFATC,NFAT Proteins,Transcription Factor NF-AT,NF-AT, Transcription Factor,Transcription Factor NF AT,Nuclear Factor of Activated T-Cells, Cytoplasmic,Nuclear Factor of Activated T Cells, Cytoplasmic,Nuclear Factors of Activated T-Cells,Nuclear Factors of Activated T Cells,NF-AT Proteins,NF AT Proteins,NFATC Proteins,NFAT Transcription Factor 4,NFAT4 Protein,Nuclear Factor of Activated T-Cells, Cytoplasmic 3 Protein,Nuclear Factor of Activated T Cells, Cytoplasmic 3 Protein,NFATC3 Transcription Factor,Factor, NFATC3 Transcription,Transcription Factor, NFATC3,NFATx Protein,NF-AT4 Protein,NF AT4 Protein,NFATC3 Protein,NFAT Transcription Factor 2,NFAT-2 Protein,NFAT 2 Protein,Nuclear Factor of Activated T-Cells, Cytoplasmic 1 Protein,Nuclear Factor of Activated T Cells, Cytoplasmic 1 Protein,NFATC1 Protein,NFATC1 Transcription Factor,Factor, NFATC1 Transcription,Transcription Factor, NFATC1,NF-ATc1 Protein,NF ATc1 Protein,NFAT2 Protein,NFAT Transcription Factor 3,NFATC4 Transcription Factor,Transcription Factor, NFATC4,NFAT3 Protein,NFATC4 Protein,Nuclear Factor of Activated T-Cells, Cytoplasmic 4 Protein,Nuclear Factor of Activated T Cells, Cytoplasmic 4 Protein,NF-AT3 Protein,NF AT3 Protein,NFAT Transcription Factor 5,Nuclear Factor of Activated T-Cells 5 Protein,Nuclear Factor of Activated T Cells 5 Protein,OREBP Protein,Osmotic Response Element Binding Protein,NFATL1 Protein,Tonicity-Responsive Enhancer-Binding Protein,Tonicity Responsive Enhancer Binding Protein,NFAT5 Protein,NFATz Protein,TonEBP Protein,NFAT Transcription Factor 1,NFATC2 Transcription Factor,Factor, NFATC2 Transcription,Transcription Factor, NFATC2,NFAT1 Protein,NFATC2 Protein,Nuclear Factor of Activated T-Cells, Cytoplasmic 2 Protein,Nuclear Factor of Activated T Cells, Cytoplasmic 2 Protein,NFAT-1 Protein,NFAT 1 Protein

Description
NFATC Transcription Factors: A family of transcription factors characterized by the presence of highly conserved calcineurin- and DNA-binding domains. NFAT proteins are activated in the CYTOPLASM by the calcium-dependent phosphatase CALCINEURIN. They transduce calcium signals to the nucleus where they can interact with TRANSCRIPTION FACTOR AP-1 or NF-KAPPA B and initiate GENETIC TRANSCRIPTION of GENES involved in CELL DIFFERENTIATION and development. NFAT proteins stimulate T-CELL activation through the induction of IMMEDIATE-EARLY GENES such as INTERLEUKIN-2.



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