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Illness finder is a diagnostic medicine tool for educational purpose that looks up your patients' health conditions or symptoms and diagnosis and find diseases or illnesses based on chosen gender, age, risk factors, illness, signs, symptoms and prevalence. Illnessfinder is inspired by Evidence based medicine (EMB) and healthcare that aims to apply the best (most reliable) knowledge that is available at decision time. Illnessfinder aims to free up time for the therapeutic dialogue and ensure quality at the evidence based practice, uniting proven medical findings and clinical evidence with systematised data technology.
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| Semaphorins | Legal notice |
Other terms
Semaphorin,Class 2 Semaphorins,Semaphorins, Class 2,Semaphorin-2,Semaphorin 2,Class 3 Semaphorins,Semaphorins, Class 3,Semaphorin-3,Semaphorin 3,Class V Semaphorins,Semaphorins, Class V,V Semaphorins, Class,Semaphorin-V,Class 5 Semaphorins,Semaphorins, Class 5,Semaphorin-5,Class 6 Semaphorins,Semaphorins, Class 6,Semaphorin-6,Semaphorin 6,Class 7 Semaphorins,Semaphorins, Class 7,Semaphorin-7,Semaphorin 7,Class 1 Semaphorins,Semaphorins, Class 1,Sema 1,Semaphorin-1,Semaphorin 1,Class 4 Semaphorins,Semaphorins, Class 4,Semaphorin-4,Semaphorin 4
Description
Semaphorins: A family of proteins that mediate axonal guidance. Semaphorins act as repulsive cues for neuronal GROWTH CONES and bind to receptors on their filopodia. At least 20 different molecules have been described and divided into eight classes based on domain organization and species of origin. Classes 1 and 2 are invertebrate, classes 3-7 are vertebrate, and class V are viral. Semaphorins may be secreted (classes 2, 3, and V), transmembrane (classes 1, 4, 5, and 6), or membrane-anchored (class 7). All semaphorins possess a common 500-amino acid extracellular domain which is critical for receptor binding and specificity, and is also found in plexins and scatter factor receptors. Their C termini are class-specific and may contain additional sequence motifs.
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