Other terms
Cholesterol 7 alpha Hydroxylase,Cholesterol 7alpha-Hydroxylase,Cholesterol 7alpha Hydroxylase,Cholesterol-7-Hydroxylase,Cholesterol 7 Hydroxylase,Cytochrome P450 7,CYP 7A,CYP7,CYP7A,Cytochrome P-450 CYP7,Cytochrome P 450 CYP7,Cholesterol 7-alpha-Monooxygenase,Cholesterol 7 alpha Monooxygenase,CYP 7
Description
Cholesterol 7-alpha-Hydroxylase: A membrane-bound cytochrome P450 enzyme that catalyzes the 7-alpha-hydroxylation of CHOLESTEROL in the presence of molecular oxygen and NADPH-FERRIHEMOPROTEIN REDUCTASE. This enzyme, encoded by CYP7, converts cholesterol to 7-alpha-hydroxycholesterol which is the first and rate-limiting step in the synthesis of BILE ACIDS.
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