Mannose-Binding Protein-Associated Serine Proteases | Legal notice |
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Other terms
Mannose-Binding Protein-Associated Serine Protease,Mannose Binding Protein Associated Serine Protease,MBP-Associated Serine Protease,MBP Associated Serine Protease,Serine Protease, MBP-Associated,MASPs,Mannan-Binding Lectin Serine Proteases,Mannan Binding Lectin Serine Proteases,MBL-Associated Serine Proteases,MBL Associated Serine Proteases,Serine Proteases, MBL-Associated,MASP Proteases,Proteases, MASP,MASP-Related Protein,MASP Related Protein,Protein, MASP-Related,MBP-Associated Serine Protease-Related Protein,MBP Associated Serine Protease Related Protein
Description
Mannose-Binding Protein-Associated Serine Proteases: Serum serine proteases which participate in COMPLEMENT ACTIVATION. They are activated when complexed with the MANNOSE-BINDING LECTIN, therefore also known as Mannose-binding protein-Associated Serine Proteases (MASPs). They cleave COMPLEMENT C4 and COMPLEMENT C2 to form C4b2a, the CLASSICAL PATHWAY C3 CONVERTASE.
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