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| Isocitrate Dehydrogenase | Legal notice |
Other terms
Dehydrogenase, Isocitrate,NAD Isocitrate Dehydrogenase,Dehydrogenase, NAD Isocitrate,Isocitrate Dehydrogenase, NAD,Isocitrate Dehydrogenase (NAD+),Isocitrate Dehydrogenase-I,Isocitrate Dehydrogenase I
Description
Isocitrate Dehydrogenase: An enzyme of the oxidoreductase class that catalyzes the conversion of isocitrate and NAD+ to yield 2-ketoglutarate, carbon dioxide, and NADH. It occurs in cell mitochondria. The enzyme requires Mg2+, Mn2+; it is activated by ADP, citrate, and Ca2+, and inhibited by NADH, NADPH, and ATP. The reaction is the key rate-limiting step of the citric acid (tricarboxylic) cycle. (From Dorland, 27th ed) (The NADP+ enzyme is EC 1.1.1.42.) EC 1.1.1.41.
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Legal notice
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