Other terms
Eposide,Demethyl Epipodophyllotoxin Ethylidine Glucoside,Eposin,Tedec Meiji Brand of Etoposide,Pharmachemie Brand of Etoposide,Etomedac,Medac Brand of Etoposide,Eto-GRY,Eto GRY,Gry Brand of Etoposide,Etopos,Lemery Brand of Etoposide,Etoposide Pierre Fabre,Pierre Fabre Brand of Etoposide,Etoposide Teva,Teva Brand of Etoposide,Etoposide, (5a alpha)-Isomer,Etoposide, (5a alpha,9 alpha)-Isomer,Etoposide, (5S)-Isomer,Etoposide, alpha-D-Glucopyranosyl Isomer,Etoposide, alpha D Glucopyranosyl Isomer,alpha-D-Glucopyranosyl Isomer Etoposide,Etoposido Ferrer Farma,Ferrer Brand of Etoposide,Exitop,Baxter Oncology Brand of Etoposide,Lastet,Sanfer Brand of Etoposide,Prasfarma Brand of Etoposide,NSC-141540,NSC 141540,NSC141540,Onkoposid,Onkoworks Brand of Etoposide,Riboposid,ribosepharm Brand of Etoposide,Toposar,Pharmacia Brand of Etoposide,Eto CS,Vepesid,Bristol-Myers Squibb Brand of Etoposide,Bristol Myers Squibb Brand of Etoposide,Bristol-Myers Brand of Etoposide,Bristol Myers Brand of Etoposide,VP 16-213,VP 16 213,VP 16213,VP-16,VP 16,VP16,Vépéside-Sandoz,Vépéside Sandoz,Novartis Brand of Etoposide,Celltop,Baxter Brand of Etoposide
Description
Etoposide: A semisynthetic derivative of PODOPHYLLOTOXIN that exhibits antitumor activity. Etoposide inhibits DNA synthesis by forming a complex with topoisomerase II and DNA. This complex induces breaks in double stranded DNA and prevents repair by topoisomerase II binding. Accumulated breaks in DNA prevent entry into the mitotic phase of cell division, and lead to cell death. Etoposide acts primarily in the G2 and S phases of the cell cycle.
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