Other terms
Receptor, erbB 2,erbB-2 Receptor,neu Proto-Oncogene Protein,Proto-Oncogene Protein, neu,neu Proto Oncogene Protein,neu Receptor,Oncogene Protein HER-2,Oncogene Protein HER 2,p185(c-neu),Proto-Oncogene Protein HER-2,Proto Oncogene Protein HER 2,erbB-2 Receptor Protein-Tyrosine Kinase,erbB 2 Receptor Protein Tyrosine Kinase,Proto-Oncogene Proteins c-erbB-2,Proto Oncogene Proteins c erbB 2,Receptor, neu,Receptors, erbB-2,Receptors, erbB 2,erbB-2 Receptors,c-erbB-2 Protein,c erbB 2 Protein,erbB-2 Proto-Oncogene Protein,Proto-Oncogene Protein, erbB-2,erbB 2 Proto Oncogene Protein,HER-2 Proto-Oncogene Protein,HER 2 Proto Oncogene Protein,Proto-Oncogene Protein, HER-2,Proto-Oncogene Protein p185(neu)
Description
Receptor, erbB-2: A cell surface protein-tyrosine kinase receptor that is found to be overexpressed in a significant number of adenocarcinomas. It has extensive homology to and can heterodimerize with the EGF receptor (RECEPTOR, EPIDERMAL GROWTH FACTOR), the erbB-3 receptor (RECEPTOR, ERBB-3) and the erbB-4 receptor. Activation of the erbB-2 receptor occurs during heterodimer formation with a ligand-bound erbB receptor family members.
Pervious tree
Next tree
Other locations in tree
Legal notice
The U.S. National Library of Medicine is the creator, maintainer, and provider of the data above.
The version of the data is 2010 MeSH. Last reviewed April 26, 2010. No modification has been made in the content of the file.
Neither the United States Government, nor any of its agencies, contractors, subcontractors or employees makes any warranties, expressed or implied, with respect to data contained in the database, and, furthermore, assumes no legal liability for any party's use, or the results of such use, of any part of the database.
You will not assert any proprietary rights to any portion of the database, or represent the database or any part thereof to anyone as other than a United States Government database.
The MeSH data carry an international copyright outside the United States, its Territories or Possessions. These terms and conditions are in effect as long as the user retains any of the MeSH data obtained from this site.